https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Disturbances in PP2A methylation and one-carbon metabolism compromise Fyn distribution, neuritogenesis, and APP regulation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45196 Wed 26 Oct 2022 15:23:03 AEDT ]]> Personal reputation and the organization https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25345 Wed 11 Apr 2018 13:52:04 AEST ]]> Lipopolysaccharide stimulation of trophoblasts induces corticotropin-releasing hormone expression through MyD88 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:5238 Sat 24 Mar 2018 07:44:17 AEDT ]]> NGF and ProNGF: regulation of neuronal and neoplastic responses through receptor signaling https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27076 Sat 24 Mar 2018 07:40:44 AEDT ]]> Market segmentation and non-uniform Shariah standards in Islamic finance https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29294 Sat 24 Mar 2018 07:34:25 AEDT ]]> The control of meiotic maturation in mammalian oocytes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20165 Mon 24 Aug 2015 15:22:23 AEST ]]> Transcript profiling identifies gene cohorts controlled by each signal regulating trans-differentiation of epidermal cells of Vicia faba Cotyledons to a transfer cell phenotype https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32463 2+ regulates wall labyrinth assembly. To identify gene cohorts regulated by each signal, a RNA- sequencing study was undertaken using Vicia faba cotyledons. When cotyledons are placed in culture, their adaxial epidermal cells spontaneously undergo trans-differentiation to epidermal TCs (ETCs). Expressed genes encoding proteins central to wall labyrinth formation (signaling, intracellular organization, cell wall) and TC function of nutrient transport were assembled. Transcriptional profiles identified 9,742 annotated ETC-specific differentially expressed genes (DEGs; Log₂fold change > 1; FDR p ≤ 0.05) of which 1,371 belonged to signaling (50%), intracellular organization (27%), cell wall (15%) and nutrient transporters (9%) functional categories. Expression levels of 941 ETC-specific DEGs were found to be sensitive to the known signals regulating ETC trans-differentiation. Significantly, signals acting alone, or in various combinations, impacted similar numbers of ETC-specific DEGs across the four functional gene categories. Amongst the signals acting alone, H₂O₂ exerted most influence affecting expression levels of 56% of the ETC-specific DEGs followed by Ca²⁺ (21%), auxin (18%) and ethylene (5%). The dominance by H₂O₂ was evident across all functional categories, but became more attenuated once trans-differentiation transitioned into WI papillae formation. Amongst the eleven signal combinations, H₂O₂/Ca²⁺ elicited the greatest impact across all functional categories accounting for 20% of the ETC-specific DEG cohort. The relative influence of the other signals acting alone, or in various combinations, varied across the four functional categories and two phases of wall labyrinth construction. These transcriptome data provide a powerful information platform from which to examine signal transduction pathways and how these regulate expression of genes encoding proteins engaged in intracellular organization, cell wall construction and nutrient transport.]]> Mon 23 Sep 2019 12:07:21 AEST ]]> An update on phloem transport: a simple bulk flow under complex regulation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32242 Mon 23 Sep 2019 10:54:37 AEST ]]> Protein phosphatase 2A: more than a passenger in the regulation of epithelial cell-cell junctions https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42190 Fri 19 Jul 2024 08:25:28 AEST ]]> Reputation Transfer https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47857 Fri 03 Feb 2023 10:51:48 AEDT ]]>